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63 L/h Lab Ultrapure Water System RNase DNase Pyrogen Free

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Designed for genomics, molecular biology, cell culture, and high-demand analytical laboratories, this high-throughput integrated ultrapure water purification system produces both Grade 3 reverse osmosis (RO) water and Type 1 (18.25 MΩ·cm) ultrapure water directly from municipal tap water. Boasting an output capacity of 63 liters per hour at 25°C and an instantaneous dispense speed of 2.0 L/min, the unit easily satisfies the peak daily water demands of multiple concurrent laboratory workbenches.


Seven-Stage Cascade Purification with 5000 Da Ultrafiltration

The purification architecture utilizes a comprehensive multi-barrier process train: PF + AC + RO + UV + DI + UF + TF.

  • A dual pretreatment purification column (LSE-PPC) removes particulate sediment, suspended rust, colloidal dirt, and chlorine.

  • A high-capacity 400 GPD reverse osmosis membrane rejects over 99% of dissolved ions, dissolved heavy metals, and macromolecular organics above 200 Daltons.

  • A dual-wavelength (185 nm & 254 nm) UV photolysis module decomposes residual organics down to total organic carbon (TOC) levels under 3 ppb while sanitizing microbial contaminants.

  • Dual continuous ultrapurification polishing modules (LSE-UP2) packed with virgin nuclear-grade resins achieve 18.25 MΩ·cm resistivity at 25°C and heavy metals under 0.1 ppb across a 10,000 to 15,000-liter service capacity.

  • A MWCO 5000 Dalton ultrafiltration (UF) cartridge eliminates trace endotoxins, pyrogens (< 0.001 Eu/mL), RNases (< 0.004 ng/mL), and DNases (< 0.024 pg/μL).

  • A final 0.2 μm point-of-use microfilter captures terminal particulates (< 1/mL) and reduces bacteria to less than 0.01 cfu/mL.

Intelligent Timed, Qualitative Dispensing and Dual-Loop Quality Verification

Operating via an intuitive digital controller, the unit supports manual dispensing, timed automatic dispensing (freely adjustable from 1 to 60 minutes), and qualitative dispensing (user-selectable from 0.1 to 18.25 MΩ·cm). Built-in high-precision instrumentation conducts two-way online monitoring of RO permeate conductivity and ultrapure water resistivity with automatic temperature compensation (0.1°C sensitivity; cell constants of 1.0 cm⁻¹ for conductivity and 0.01 cm⁻¹ for resistivity).

Automated Membrane Preservation and Administrative Access Security

To suppress crystalline membrane fouling without chemical additions, the system runs automated 2-hour cyclical flushes alongside manual bypass options. Consumable life tracking algorithms monitor cumulative runtime and treated volume across all filter cartridges, alerting operators when replacements are needed. Two-tier password protection (Administrator and User levels) locks down critical operational parameters, preventing accidental changes to system configuration or calibration profiles.


Technical Specifications

Technical CategoryParameter ItemDetailed Specification Value
System ArchitectureTreatment Train FlowPF + AC + RO + UV + DI + UF + TF (7-stage complete process)
Stage 1 PretreatmentLSE-PPC dual pretreatment purification column (1 unit)
Stage 2 Reverse OsmosisLSE-RO-400GPD reverse osmosis membrane (1 unit)
Stage 3 UV Oxidation185 nm & 254 nm dual-wavelength UV lamp tube (1 unit)
Stage 4 UltrapurificationLSE-UP2 dual continuous ultrapurification columns (2 units)
Stage 5 UltrafiltrationLSE-UF-5000D UF module (MWCO 5000 Daltons, 1 unit)
Stage 6 Terminal FiltrationLSE-TF-0.2μm point-of-use microfiltration filter (1 unit)
Raw Water FeedWater Supply QualityMunicipal tap water
Feed Water Conductivity< 400 μS/cm (external water softener recommended if > 400 μS/cm)
Operating Temperature5°C to 45°C
Inlet Water Pressure1.0 to 4.0 kgf/cm²
Pure Water (Grade 3)Continuous Production Rate63 Liters / hour (measured at 25°C, 50 psi, 15% recovery ratio)
Instantaneous Dispensing Flow2.0 Liters / minute (with pressurized storage vessel)
Permeate Electrical Conductivity≤ Raw tap water conductivity × 2% to 4%
Organic Compound Rejection> 99% (for organic molecules with MW > 200 Daltons)
Particulate & Bacterial Rejection> 99% rejection rate
Ultrapure Water (Type 1)Electrical Resistivity (at 25°C)18.25 MΩ·cm
Total Organic Carbon (TOC)< 3 ppb
Heavy Metal Ion Content< 0.1 ppb
Endotoxin / Pyrogen Content< 0.001 Eu/mL
Ribonuclease (RNases)< 0.004 ng/mL
Deoxyribonuclease (DNases)< 0.024 pg/μL
Bacterial Residual Count< 0.01 cfu/mL
Particulates (> 0.22 μm)< 1 / mL
Dispensing & MonitoringDispensing Outlet OptionsDual dedicated ports: RO pure water and UP ultrapure water
Timed Volumetric DispensingFreely adjustable from 1 to 60 minutes
Qualitative Dispensing LimitUser-definable threshold from 0.1 to 18.25 MΩ·cm
Online Sensor ConfigurationTwo-way online sensors: RO conductivity & UP resistivity with auto-temp compensation
Sensor Cell ConstantsConductivity constant: 1.0 cm⁻¹; Resistivity constant: 0.01 cm⁻¹
Security & OperationalPassword Access LevelsTwo-tier security passwords (Factory / User)
RO Membrane PreservationAutomated 2-hour cyclical flushing plus manual forced-flush mode
System Status IndicatorsRunning status LED, Alarm indicator LED, Water tank full LED
Standard Package InclusionsMain chassis, full consumable pack, dispenser, 25L/40L tank, accessory kit
Physical & ElectricalElectrical Supply & Power DrawAC 220V, 50 Hz; 120W
External Dimensions (H × W × D)970 mm × 420 mm × 420 mm
Net Machine WeightApprox. 50 kg

Estimated Consumable Lifecycle Overview

Consumable Part ModelFunctional Component DescriptionTypical QuantityEstimated Operational Lifespan
LSE-PPCDual Pretreatment Purification Column1 unit4 – 6 months
LSE-RO-400GPDHigh-Capacity 400 GPD RO Membrane1 unit1 – 2 years
LSE-UVlamp-185&254nmDual-Wavelength UV Oxidation Tube1 unitApprox. 9,000 hours
LSE-UP2Dual Ultrapurification Polishing Modules2 units10,000 – 15,000 Liters of UP water
LSE-UF-5000DMWCO 5000D Ultrafiltration Module1 unit2 – 3 years
LSE-TF-0.2μm0.2 μm Sterile Terminal Filter Capsule1 unitApprox. 1 year

Frequently Asked Questions (FAQ)

1. What distinct water purity grades does this system produce?

The system outputs Grade 3 RO pure water for glassware rinsing, autoclave feed, and general prep, as well as Type 1 (18.25 MΩ·cm) ultrapure water free of pyrogens and nucleases.

2. Why is this model particularly recommended for life science and cell culture?

It features a 5000 Dalton ultrafiltration module that eliminates pyrogens (< 0.001 Eu/mL), RNases (< 0.004 ng/mL), and DNases (< 0.024 pg/μL), preventing biological degradation in sensitive cell lines and PCR runs.

3. What is the daily output capacity of the 63 L/h generation module?

Generating 63 liters per hour at 25°C, the system produces over 500 to 1,000 liters of purified water daily, serving large analytical teams and high-throughput research suites.

4. How does the timed dispensing feature prevent benchtop overflows?

Users can configure automatic dispensing from 1 to 60 minutes, allowing staff to fill large carboys without standing by the unit, as it shuts off automatically when the timer elapses.

5. How does the qualitative dispensing setting protect sensitive experiments?

Operators can set a minimum acceptable resistivity cutoff between 0.1 and 18.25 MΩ·cm, ensuring the dispenser delivers water only when analytical purity meets the programmed threshold.

6. What parameters are actively monitored by the dual-sensor system?

The system continuously measures RO permeate conductivity, Type 1 ultrapure water resistivity, and fluid temperature, applying automatic temperature compensation with 0.1°C resolution.

7. How often does the reverse osmosis membrane execute automatic cleaning?

The controller initiates an automatic high-velocity membrane flush every 2 hours of runtime to remove accumulated mineral deposits, supplemented by a manual on-demand flush option.

8. What storage tank capacities can be connected to this system?

The unit connects to standard 25 L, 40 L, 75 L, or 100 L pressurized bladder tanks, as well as 50 to 1,000 L atmospheric level-sensing reservoirs equipped with distribution pumps and air filters.

9. How do administrative passwords prevent unauthorized setting alterations?

The software includes a two-tier password hierarchy (Factory and User levels) that locks down calibration limits, sensor offsets, and flushing intervals against unauthorized tampering.

10. What optional accessories can be added to enhance lab safety and convenience?

Available options include an external automatic water softener for hard municipal water, an active floor leak detector that automatically cuts the inlet line, and a hands-free foot pedal dispenser.

11. How does the system inform users of cartridge exhaustion?

The software tracks cumulative operating hours and processed liters across each cartridge, displaying popup warnings when pre-set service milestones are reached.

12. What are the feed tap water prerequisites for proper installation?

The system requires standard municipal tap water at 5°C to 45°C, 1.0 to 4.0 kgf/cm² inlet pressure, and conductivity below 400 μS/cm (water exceeding 400 μS/cm requires a pre-softener).

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