High throughput ultrasonic DNA interrupter non-contact break cell homogenizer avoid cross contamination

The Non-contact Ultrasonic DNA Homogenizer employs innovative technology to disrupt and homogenize biological samples without direct physical contact, offering a gentle and effective method for preserving sample integrity. This advanced instrument operates on the principle of non-contact ultrasonic waves, ensuring optimal functionality and applications in molecular biology research.

Principle: Utilizing non-contact ultrasonic waves, the homogenizer generates acoustic cavitation in the sample, leading to controlled disruption of cellular structures. The non-contact nature of the ultrasonic technology minimizes the risk of contamination, preserving the integrity of delicate biological structures, including DNA.

Key Features:

1. Non-Contact Ultrasonic Disruption: The homogenizer operates without direct physical contact with the sample, minimizing the risk of cross-contamination and ensuring the preservation of sample purity and integrity.

2. Gentle Sample Processing: The non-contact ultrasonic waves provide a gentle disruption process, preventing excessive heat generation and minimizing the risk of DNA shearing and degradation, thereby maintaining the quality of genetic material.

3. Customizable Parameters: Researchers can customize ultrasonic power, duration, and other parameters, allowing for precise optimization of the disruption process for various sample types, ensuring flexibility in experimental design.

Applications:

The Non-contact Ultrasonic DNA Homogenizer is particularly suitable for various applications in molecular biology research:

1. DNA Extraction: Ideal for preparing samples for DNA extraction, the homogenizer ensures the efficient release of intact DNA from cells and tissues, essential for downstream applications like PCR, sequencing, and genetic analysis.

2. RNA and Protein Extraction: The non-contact disruption method is also applicable for obtaining high-quality RNA and proteins from biological samples, contributing to diverse molecular biology studies.

3. Cell Homogenization: Well-suited for homogenizing cells in a non-invasive manner, the homogenizer supports a range of cellular studies, including gene expression analysis and cell-based assays.

The Non-contact Ultrasonic DNA Homogenizer combines the advantages of non-contact ultrasonic technology with customizable parameters, making it an innovative and versatile tool for researchers seeking gentle and contamination-free disruption of biological samples for various molecular biology applications.

NMDNA-32S Non-contact Ultrasonic DNA Interrupter

Product introduction:

NMDNA-32S Non-contact ultrasonic DNA interrupter uses an isothermal, non-contact method to break, homogenize and mix 32 samples at a time through a centrifuge tube. It can be used for asepsis, ultramicro breakage and chromosome breakage, specially customized for the pre-treatment of second-generation sequencing DNA samples and chromatin immunoprecipitation experiment samples, at least 5UL trace samples, suitable for precious samples.

Product features:

1. High throughput: up to 32 samples can be processed simultaneously at one time, and the experimental efficiency is high.

2. Avoid cross contamination: there is no need to operate the probe frequently, and various samples are in a separate fully enclosed test tube to avoid cross contamination. At the same time, in a closed environment, it can effectively avoid the potential biological hazards caused by the diffusion of aerosol or foam generated during the ultrasonic process into the environment.

3. Good repeatability and high accuracy: ultrasonic parameter setting is flexible, experimental steps are standardized, experimental repeatability is good, and the results are highly reliable.

4. Good sample protection: The use of 4℃ low temperature water bath ultrasound, uniform energy distribution, ultrasonic effect is complete, in low temperature environment, to avoid sample denaturation.

5. Rich configuration: 0.1mL-15mL variety of adapters can be configured to meet the needs of a variety of samples.

6. Low experimental cost: no need for special consumables, the experimental cost is relatively low.

Working principle:

Through piezoelectric converters, electrical signals are converted into high-frequency acoustic signals, creating millions of molecular "holes" that utilize "voids. The instantaneous fluid shear force generated by the hole's enlarging and breaking in a few seconds interrupts, homogenizes, and mixes the sample in an isothermal, non-contact manner.

Application fields:

1. DNA fragmentation

2. RNA fragmentation

3. ChIP assay (Chromatin immunoprecipitation) sample pretreatment

4. Fragmentation of bacteria and cells and extraction of membrane proteins

5. Crushing, homogenization, emulsification of mold spores, etc

6. Ultrasonic treatment of valuable reagents

7. High-throughput sequencer sample preprocessing

Technical parameters:

1. The sample is broken by ultrasonic focusing principle.

2. The whole process of broken cell bacteria samples are in a completely closed state to avoid cross-contamination of samples.

3. Ultrasonic DNA interrupter is suitable for ultra-trace EP tube, minimum can handle 5ul samples, suitable for precious samples.

4. It can be used for pre-processing of sequencing DAN samples and CHIP chromosome immunoprecipitation samples.

5. Nucleic acid sample processing range 100bp-1kb.

6. The sample does not touch the ultrasonic probe and is broken in the closed tube throughout.

7. Control mode: real-time display of synchronous touch screen operation phase/frequency/waveform.

8. Control screen size: ≥7 inches touch screen.

9. Frequency control: automatic

tracking.

10. Temperature system: temperature probe real-time detection of ice bath, over temperature automatic protection reminder.

11. Processing capacity: up to 32 samples (200ul).

12. Bilingual support: both English and Chinese desktop display.

13. Adjustable amplitude: 1-100%.

14. Data preservation: up to 20 data can be saved.

15. Amplitude adjustment: 0-100%.

16. Phase/frequency: display simultaneously.

17. Power adjustable: 1-100% (total power 1000W).

18. Refrigeration system: external supporting.

19. Cooling temperature: -5℃ to 100℃.

20. Time control: working time 0.1S-999min can be adjusted. Intermittent time 0.1S-999M adjustable.

21. Working slot size：240x150x100mm.

22. The shell material of the whole machine: the ABS plastic shell with open mold is formed.

23. Overall dimensions (L*W*H)：578*360*370mm.

Configuration list:

1. The main machine 1 set (including cooling circulation system).

2. 200ul adapter/can handle up to 32 samples at a time.

3. 500ul adapter/can handle up to 16 samples at a time.

4. 1.5/2mL adapter/can handle up to 10 samples at a time.

5. 5mL adapter/can handle up to 5 samples at a time.

NMDNA-64S Non-contact Ultrasonic DNA Interrupter

Product introduction:

NMDNA-64S Non-contact ultrasonic DNA interrupter uses an isothermal, non-contact method to break, homogenize and mix 64 samples at a time through a centrifuge tube. It can be used for asepsis, ultramicro breakage and chromosome breakage, specially customized for the pre-treatment of second-generation sequencing DNA samples and chromatin immunoprecipitation experiment samples, at least 5UL trace samples, suitable for precious samples.

Product features:

1. High throughput: up to 64 samples can be processed simultaneously at one time, and the experimental efficiency is high.

2. Avoid cross contamination: there is no need to operate the probe frequently, and various samples are in a separate fully enclosed test tube to avoid cross contamination. At the same time, in a closed environment, it can effectively avoid the potential biological hazards caused by the diffusion of aerosol or foam generated during the ultrasonic process into the environment.

3. Good repeatability and high accuracy: ultrasonic parameter setting is flexible, experimental steps are standardized, experimental repeatability is good, and the results are highly reliable.

4. Good sample protection: The use of 4℃ low temperature water bath ultrasound, uniform energy distribution, ultrasonic effect is complete, in low temperature environment, to avoid sample denaturation.

5. Rich configuration: 0.1mL-15mL variety of adapters can be configured to meet the needs of a variety of samples.

6. Low experimental cost: no need for special consumables, the experimental cost is relatively low.

Working principle:

Through piezoelectric converters, electrical signals are converted into high-frequency acoustic signals, creating millions of molecular "holes" that utilize "voids.The instantaneous fluid shear force generated by the hole's enlarging and breaking in a few seconds interrupts, homogenizes, and mixes the sample in an isothermal, non-contact manner.

Application fields:

1. DNA fragmentation

2. RNA fragmentation

3. ChIP assay (Chromatin immunoprecipitation) sample pretreatment

4. Fragmentation of bacteria and cells and extraction of membrane proteins

5. Crushing, homogenization, emulsification of mold spores, etc

6. Ultrasonic treatment of valuable reagents

7. High-throughput sequencer sample preprocessing

Technical parameters:

1. The sample is broken by ultrasonic focusing principle.

2. The whole process of broken cell bacteria samples are in a completely closed state to avoid cross-contamination of samples.

3. Ultrasonic DNA interrupter is suitable for ultra-trace EP tube, minimum can handle 5ul samples, suitable for precious samples.

4. It can be used for pre-processing of sequencing DAN samples and CHIP chromosome immunoprecipitation samples.

5. Nucleic acid sample processing range 100bp-1kb.

6. The sample does not touch the ultrasonic probe and is broken in the closed tube throughout.

7. Control mode: real-time display of synchronous touch screen operation phase/frequency/waveform.

8. Control screen size: ≥7 inches touch screen.

9. Frequency control: automatic tracking.

10. Temperature system: temperature probe real-time detection of ice bath, over temperature automatic protection reminder.

11. Processing capacity: up to 64 samples (200ul)

12. Bilingual support: both English and Chinese desktop display.

13. Adjustable amplitude: 1-100%.

14. Data preservation: up to 20 data can be saved.

15. Amplitude adjustment: 0-100%.

16. Phase/frequency: display simultaneously.

17. Power adjustable: 1-100% (total power 1000W).

18. Refrigeration system: external supporting.

19. Cooling temperature: -5℃ to 100℃.

20. Time control: working time 0.1S-999min can be adjusted. Intermittent time 0.1S-999M adjustable.

21. Working slot size：240x150x100mm；

22. The shell material of the whole machine: the ABS plastic shell with open mold is formed.

23. Overall dimensions (L*W*H)：578*360*370mm.

Configuration list:

1. The main machine 1 set (including cooling circulation system).

2. 200ul adapter/can handle up to 64 samples at a time.

3. 500ul adapter/can handle up to 32 samples at a time.

4. 1.5/2mL adapter/can handle up to 20 samples at a time.

5. 5mL adapter/can handle up to 10 samples at a time.

NMDNA-96S Non-contact Ultrasonic DNA Interrupter

Product introduction:

NMDNA-96S Non-contact ultrasonic DNA interrupter uses an isothermal, non-contact method to break, homogenize and mix 96 samples at a time through a centrifuge tube. It can be used for asepsis, ultramicro breakage and chromosome breakage, specially customized for the pre-treatment of second-generation sequencing DNA samples and chromatin immunoprecipitation experiment samples, at least 5UL trace samples, suitable for precious samples.

Product features:

1. High throughput: up to 96 samples can be processed simultaneously at one time, and the experimental efficiency is high.

2. Avoid cross contamination: there is no need to operate the probe frequently, and various samples are in a separate fully enclosed test tube to avoid cross contamination. At the same time, in a closed environment, it can effectively avoid the potential biological hazards caused by the diffusion of aerosol or foam generated during the ultrasonic process into the environment.

3. Good repeatability and high accuracy: ultrasonic parameter setting is flexible, experimental steps are standardized, experimental repeatability is good, and the results are highly reliable.

4. Good sample protection: The use of 4℃ low temperature water bath ultrasound, uniform energy distribution, ultrasonic effect is complete, in low temperature environment, to avoid sample denaturation.

5. Rich configuration: 0.1mL-15mL variety of adapters can be configured to meet the needs of a variety of samples.

6. Low experimental cost: no need for special consumables, the experimental cost is relatively low.

Working principle:

Through piezoelectric converters, electrical signals are converted into high-frequency acoustic signals, creating millions of molecular "holes" that utilize "voids.The instantaneous fluid shear force generated by the hole's enlarging and breaking in a few seconds interrupts, homogenizes, and mixes the sample in an isothermal, non-contact manner.

Application fields:

1. DNA fragmentation

2. RNA fragmentation

3. ChIP assay (Chromatin immunoprecipitation) sample pretreatment

4. Fragmentation of bacteria and cells and extraction of membrane proteins

5. Crushing, homogenization, emulsification of mold spores, etc

6. Ultrasonic treatment of valuable reagents

7. High-throughput sequencer sample preprocessing

Technical parameters:

1. The sample is broken by ultrasonic focusing principle.

2. The whole process of broken cell bacteria samples are in a completely closed state to avoid cross-contamination of samples.

3. Ultrasonic DNA interrupter is suitable for ultra-trace EP tube, minimum can handle 5ul samples, suitable for precious samples.

4. It can be used for pre-processing of sequencing DAN samples and CHIP chromosome immunoprecipitation samples.

5. Nucleic acid sample processing range 100bp-1kb.

6. The sample does not touch the ultrasonic probe and is broken in the closed tube throughout.

7. Control mode: real-time display of synchronous touch screen operation phase/frequency/waveform.

8. Control screen size: ≥7 inches touch screen.

9. Frequency control: automatic tracking.

10. Temperature system: temperature probe real-time detection of ice bath, over temperature automatic protection reminder.

11. Processing capacity: up to 96 samples (200ul)

12. Bilingual support: both English and Chinese desktop display.

13. Adjustable amplitude: 1-100%.

14. Data preservation: up to 20 data can be saved.

15. Amplitude adjustment: 0-100%.

16. Phase/frequency: display simultaneously.

17. Power adjustable: 1-100% (total power 1000W).

18. Refrigeration system: external supporting.

19. Cooling temperature: -5℃ to 100℃.

20. Time control: working time 0.1S-999min can be adjusted. Intermittent time 0.1S-999M adjustable.

21. Working slot size：240x150x100mm；

22. The shell material of the whole machine: the ABS plastic shell with open mold is formed.

23. Overall dimensions (L*W*H)：578*360*370mm.

Configuration list:

1. The main machine 1 set (including cooling circulation system).

2. 96-well Adapter (200ul).