ABL-X Series: Advanced In Vivo Imaging Systems

The ABL-X series represents a pinnacle in molecular imaging technology, specifically designed for non-invasive, real-time monitoring of biological processes in small animals. This series integrates ultra-sensitive detection with automated animal life-support systems, providing a comprehensive solution for oncology, immunology, and drug discovery research.

Common Series Advantages

• High-Definition Optical Path: Up to 10-megapixel resolution lenses combined with a backlit filter design significantly reduce background interference for crystal-clear signal localization.

• Integrated Touch Interface: A front-mounted touchscreen allows for seamless control of the sampling platform and real-time monitoring of instrument status.

• Advanced Life-Support Chamber: Features a polymer low-energy constant temperature mode to minimize animal hypothermia. The system includes a fully automatic lifting anesthesia platform capable of supporting up to 5 mice simultaneously.

• Intelligent Automation: Electrically driven horizontal sampling platforms and automated positioning lift stages ensure maximum operational convenience and reproducibility.

• Multimodal Fusion: Capable of high-performance RGB multicolor fluorescence, NIR (Near-Infrared) imaging, and bioluminescence, with seamless image fusion against animal contours.

  
  

  Series Comparison & Key Differences

  While both series offer high-end performance, the primary difference lies in the CCD Sensor Technology, which dictates the level of sensitivity and resolution for specific research needs.

  1. ABL-X5 Series: High-Resolution Precision

  • Sensor: Equipped with a scientific-grade deep-cooling CCD featuring a SONY ICX 695 chip.

  • Resolution: Offers a high pixel count of 2688 × 2200 with an image resolution of 600 DPI, ideal for capturing fine structural details.

  • Efficiency: Quantum efficiency exceeding 75%.

  • Best For: General bioluminescence and fluorescence applications where higher spatial resolution is required.

  2. ABL-X6 Series: Ultra-Sensitivity Powerhouse

  • Sensor: Utilizes a premier E2V Backlit CCD chip (1024 × 1024).

  • Efficiency: Achieves an industry-leading quantum efficiency of over 96%.

  • Light Capture: The backlit sensor architecture allows for significantly higher photon collection, making it the superior choice for extremely weak signals.

  • Best For: Advanced research involving deep-tissue imaging, very low-expression markers, and ultra-weak bioluminescence.

    
    

    Optional gas anesthesia system

    
    

    Application Description

    Used in tumor, gene function, drug research, gene therapy, stem cell research, inflammation, immune diseases, neurological diseases, cardiovascular diseases, metabolic diseases, new drug evaluation, toxicology and other scientific research.

    
    Imaging effect

    

    
    

    
    

    FAQs for International Clients

    1. What is the main difference between the ABL-X5 and ABL-X6?

    The core difference is the CCD chip. The ABL-X5 offers higher resolution ($2688 \times 2200$) for detailed imaging, while the ABL-X6 uses a backlit CCD with $>96\%$ quantum efficiency for maximum sensitivity when detecting ultra-weak signals.

    2. How many animals can be imaged at once?

    Both systems are designed with a large-format anesthesia platform that can comfortably accommodate 1 to 5 mice simultaneously, significantly improving throughput for large studies.

    3. Does the system support Near-Infrared (NIR) imaging?

    Yes. Both series support high-performance NIR fluorescence, which is essential for deep-tissue imaging as it reduces autofluorescence and improves photon penetration.

    4. How does the system prevent animal mortality during long experiments?

    The systems feature a polymer low-energy constant temperature life chamber. This ensures a stable thermal environment, effectively reducing the risk of animal death caused by hypothermia during anesthesia.

    5. Can this system be used for in vitro samples?

    Absolutely. Beyond live animals, the flexible lifting platform allows for high-quality imaging of 96-well plates, culture dishes, and other in vitro samples.

    6. What is the significance of the F0.85 lens?

    The F0.85 ultra-large aperture lens is one of the fastest in the industry. It allows a massive amount of light to reach the sensor, which is critical for capturing the weak photons emitted in bioluminescence.

    7. Is the image analysis software included?

    Yes, the system comes with an integrated software suite capable of signal quantification, image fusion (merging signal with animal contour), and multi-channel analysis.

    8. Can I perform multiplexing with different fluorescence colors?

    Yes. The system supports RGB multicolor fluorescence, allowing you to track multiple probes or biomarkers within the same animal using the uniquely designed multi-channel excitation source.

    9. How is the background noise managed?

    We utilize a backlit filter optical path design. By placing the filters in a specific configuration, we significantly reduce internal background interference, presenting a much clearer target signal.

    10. Is the operating system user-friendly?

    The front-mounted embedded touchscreen provides an intuitive interface for controlling the sampling platform and monitoring the instrument’s status without needing a secondary controller.

    11. What maintenance is required for the CCD camera?

    The cameras are scientific-grade deep-cooling units. They are vacuum-sealed and maintenance-free, designed to operate at very low temperatures to minimize thermal noise.

    12. Do you provide installation and training for international customers?

    We provide comprehensive technical documentation, installation guides, and video training modules. We also offer trial samples and remote technical support to ensure our global partners can operate the system with confidence.