Online Total Organic Carbon Analyzer | UV Oxidation TOC Meter TC-1700

Engineered for critical water quality monitoring in pharmaceutical biomanufacturing, semiconductor wafer fabrication, and precision chemical analysis, this Total Organic Carbon (TOC) analyzer delivers automated quantification of trace organic impurities. Available in offline benchtop and real-time online continuous monitoring configurations, the system measures purified water (PW), water for injection (WFI), microelectronics-grade rinse water, and ultrapure water (UPW) across a dynamic analytical range of 1 to 1500 ppb with an ultra-low detection limit of 1 ppb.

Reagentless UV Lamp Photolysis and Conductivity Detection

The instrument utilizes high-energy ultraviolet (UV) lamp photolysis to oxidize organic compounds into carbon dioxide without requiring hazardous chemical reagents, external acid dosing, combustion carrier gases, or expensive oxidation catalysts. This reagent-free mechanism eliminates chemical handling hazards, suppresses operating baseline noise, and reduces the consumable cost per test. High-precision flow-through conductivity sensors quantify total inorganic carbon (TIC) and total carbon (TC) states, calculating net TOC values with repeatability tolerance within ≤3% and maximum measurement tolerance within ±5%.

Rapid Analytical Turnaround and Industrial Touch Controls

Operating at a regulated fluid ingestion rate of 2 mL/min, the unit finishes complete sample oxidation cycles within 3 minutes, exhibiting an overall system response time within 10 minutes. A smart 7-inch color touchscreen interface provides intuitive instrument operation, displaying real-time conductivity changes, concentration trends, and diagnostic parameters. Single-button automated sampling protocols minimize user touchpoints and protect grab samples from ambient volatile organic carbon (VOC) contamination.

Pharmacopeial Compliance, Traceability, and High-Throughput Automation

The control architecture supports optional PC software that complies fully with FDA 21 CFR Part 11 data governance as well as USP <643>, EP 2.2.44, ChP, and JP pharmacopeial monograph standards. Featuring an internal 8GB storage memory with unrestricted time-stamped record logging, users can search historical test files by date and export datasets directly to external USB flash media or an integrated Bluetooth printer. For high-throughput laboratory testing, the platform readily integrates with an optional 20-position autosampler.

Technical Specifications

Frequently Asked Questions (FAQ)

1. What are the key differences between the offline and online TOC models?

The offline configuration is optimized for laboratory benchtop grab samples and autosampler vials, whereas the online configuration connects directly to pressurized process loops to provide automated, continuous real-time water monitoring.

2. Does this TOC analyzer require chemical reagents, acids, or carrier gases to operate?

No, the analyzer uses direct ultraviolet lamp photo-oxidation without requiring external carrier gas cylinders, hazardous acid addition, or oxidizing chemical catalysts, minimizing recurring operational expenses.

3. What critical water grades can be measured by this equipment?

The analyzer is configured to measure Water for Injection (WFI), Purified Water (PW), semiconductor microelectronics rinse water, ultrapure water (UPW), and cleaning validation rinse samples.

4. What is the lower detection limit and measuring range of the system?

The instrument provides a measuring range of 1 to 1500 ppb with an analytical detection limit of 1 ppb, suitable for sub-ppb compliance testing.

5. How long does a single TOC measurement take to complete?

A typical sample analysis finishes in 3 minutes, with overall system hydraulic and measurement response occurring within 10 minutes at a flow rate of 2 mL/min.

6. Does the software meet FDA 21 CFR Part 11 requirements?

Yes, the optional software package complies with FDA 21 CFR Part 11, providing multi-level password protection, electronic signatures, time-stamped audit trails, and secure data archiving.

7. Which international pharmacopeial standards are supported?

The testing principle and performance parameters conform to the compendial water testing mandates of the United States Pharmacopeia (USP <643>), European Pharmacopoeia (EP 2.2.44), Chinese Pharmacopoeia (ChP), and Japanese Pharmacopoeia (JP).

8. Can the system automate high-throughput batch testing of water vials?

Yes, the laboratory setup can be equipped with an optional 20-position automated water autosampler to run unattended multi-sample sequences.

9. How is test data stored and exported from the instrument?

The analyzer contains an internal 8GB memory drive that archives historical records searchable by date; files can be exported directly via a USB flash drive or printed via an integrated Bluetooth printer.

10. How does one-button sampling reduce cross-contamination?

The single-button automated fluid intake mechanism draws liquid directly from the vial or sampling port through inert tubing, preventing atmospheric volatile organic carbon (VOC) ingress and reducing operator handling errors.

11. What utility supplies are needed to install the analyzer?

The unit requires a standard single-phase electrical connection (AC 110/220V, 50/60 Hz, 100W) and an atmospheric drain; no high-pressure compressed air or specialized gas hookups are required.

12. What maintenance procedures are required for routine upkeep?

Thanks to its modular architecture, routine maintenance is limited to periodic calibration with sucrose/1,4-benzoquinone standard solutions, checking sample line cleanliness, and replacing the UV photolysis lamp at recommended service intervals.